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Medical Physiology: Principles for Clinical Medicine richly presents the physiology knowledge necessary for clinical practice. Along with the latest information on how the human body reacts to internal and external changes, the text provides a deep understanding of how physiologic systems coordinate to maintain optimal health. Emphasizing normal physiology, discussions of pathophysiology are also included to show how altered functions are involved in disease processes. This fifth edition focuses on the physiologic principles key to understanding human function, and places them clearly in their fundamental context in clinical medicine. Clinical Focus essays highlight how and where physiology relates to clinical medicine and diagnosis.